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FRIDAY MAY 10TH
THEME: LIPIDS IN IMMUNE FUNCTION
Co-Chairs: Philip Calder, University of Southampton, UK and Catherine Field, University of Alberta, Canada
09:30 – 10:00 Exhibits & Scientific Posters
10:00 – 12 noon Three Concurrent Oral Sessions
SESSION K: LIPIDS IN IMMUNOLOGY – 2
Co-Chairs: Victor Gavino, University of Montreal, and Richard Bazinet, University of Toronto, Canada
K-1: The Effect of Supplementation of a Full Term Formula with Long Chain Polyunsaturated Fatty Acids on Peripheral Immune Function.
C. Field, J. Van Aerde, and M. Clandinin, University of Alberta, Canada
K-2: Effect of Seal Oil on Joint Pain in Patients with Inflammatory Bowel Disease.
L. Froyland1, G. Arslan2, L. Brunborg1, J. Brun2, M. Valen2, 1Directorate of Fisheries, Norway; 2Haukeland University Hospital, Norway
K-3: Reduction by n-3 Polyunsaturated Fatty Acids of Inflammatory Responses Associated with Arthritis.
C.L. Curtis1, S.R. Rees1, S.M. Hurst1, C.E. Hughes1, C.M. Dent2, C. Wilson2, R. Williams2, C. Caterson1, and J.L. Harwood1; 1Cardiff University, UK 2Llandough Hospital, UK
K-4: The Effects of Plant and Marine n-3 PUFA Supplied Through Foods on Immune Function and Fatty Acid Composition in Humans.
S. Kew1, T. Banerjee1, A..M Minihane2, Y.E. Finnegan2, C.M. Williams2, P.C. Calder1, 1University of Southampton, 2University of Reading, UK
K-5: The Dose-Response Relationship Between EPA Supply and EPA in Human Mononuclear Cells.
E.A. Miles, T. Banerjee, S. Wells, and P. C. Calder, University of Southampton, UK
K-6: Fish Oil Reduces PGE2 Synthesis but Increases IFN-Gamma and IL-4 Synthesis by PBMC in Healthy Subjects.
T. Trebble, S. Wootton, E. Miles, and P. Calder, University of Southampton, UK
SESSION L: POLYUNSATURATES IN THE DIET – 1
Chair: Bjorn Rene, Pronova Biocare, Norway
L-1: Quantitative Changes in the Availability of Fats in the US Food Supply.
J.R. Hibbeln, William EM Lands, E.T. Lamoreaux, NIAAA, NIH, USA
L-2: Australian Intakes and Food Sources of Omega-6 and Omega-3 Polyunsaturated Fatty Acids.
B.J. Meyer1, P.R.C. Howe1, J.L. Lewis2, G. Milligan2, N.J. Mann3 and A.J. Sinclair3
1University of Wollongong, 2Australia/New Zealand Food Authority, 3RMIT University, Australia
L-3: Temporal Trends in Fat Intake in the US, UK and Canada.
A.M. Stephen1,2, J.E. Reid2, S Walker1, S Berg1. 1College of Pharmacy and Nutrition, University of Saskatchewan, 2CANTOX Health Sciences International, Canada
L-4: Fatty Acid Profile, Total Trans Fatty Acids and Physical Properties of Argentine Margarines.
Lilia Masson1 and Patricia Albarracin2 1Universidad de Chile, Chile 2Universidad Nacional de Tucumán, Argentina
L-5: N-3 Enriched Eggs as a Source of Essential Docosahexaenoic Acid (DHA) in the Diets of Weaning Infants.
M.A. Neumann1, J.S. Hawkes1, M. Makrides2, R.A. Gibson1, 1Flinders University, 2Child Health Research Institute, Australia
L-6: Docosahexaenoic Acid Enriched Egg Consumption Induces Accretion of Arachidonic Acid in Red Blood Cells of Elderly Patients.
Marianne Payet, Mohamed H. Esmail, Gérard Pieroni, I.N.S.E.R.M. Marseille, Elisabeth Polichetti, Gaël Le Brun, Glon Sanders, Pontivy, Lounès Adjemout, Gérard Donnarel, Centre Gérontologique Départemental, France
SESSION M: MOLECULAR ASPECTS OF LIPIDS
Chair: Anna Petroni, University of Milan, Italy
M-1: Effects of Muscle Activity on Fatty Acid Transport and Fatty Acid Transporters in Skeletal Muscle.
D. Koonen1, Jan Glatz1, J.J.F.P. Luiken1, Y. Arumugam2, A. Bonen2, 1University of Maastricht, The Netherlands, 2University of Waterloo, Canada
M-2: Ethanol and Fatty Acid Ethyl Ester as Promoters of Toxicity in Hepatitis C Virus Infected HepG2 Cells.
M. Laposata1, A. Hasaba1, G.Abel2, M. Elfahal2, V. Agnello2, 1Massachusetts General Hospital, USA; 2Lahey Clinic, USA
M-3: Acute Regulation of Fatty Acid Uptake Involves the Cellular Redistribution of Fatty Acid Translocase (FAT/CD36).
J.J.F.P. Luiken1, D.P.Y. Koonen1, J.Willems1, S.L.M. Coort1, G.J. van der Vusse1, A. Bonen2, J.F.C. Glatz1, 1Maastricht University, The Netherlands, 2University of Waterloo, Canada
M-4: Intracellular Lipid Binding Proteins Influence Cellular Lipid Metabolism.
E.J. Murphy, University of North Dakota, USA
M-5: Fatty Acid and Androgen Metabolism in X-Adrenoleukodystrophy.
A.Petroni1, M.Blasevich1, F. Roveda1, F. Riva1 and G.Uziel2, 1 University of Milan, 2Instituto Neurologico “C.Besta”, Italy
M-6: αSynuclein Oligomers Appear in Cytosolic Lipid-Rich Complexes in Vivo and in Vitro.
R. Sharon1,2,3, I. Bar-Joseph1, M.P. Frosch4, C.A. Serhan1 and D.J. Selkoe1, 1Center for Neurologic Disease, 2Brigham and Women's Hospital, 3Harvard Medical School, USA, 4MGH, USA
12 noon – 13:00 Exhibits & Scientific Posters
14:30 – 15:00 Exhibits & Scientific Posters
15:00 – 17:00 Three Concurrent Oral Sessions
SESSION N: LIPIDS IN CARDIOVASCULAR DISEASE – 2
Co-Chairs: Ken Stark, and Bruce Holub, University of Guelph, Canada
N-1: The Effect of a Low Dose of Eicosapentaenoic Acid on Serum Lipids in Normotriglyceridemic and Hypertriglyceridemic Humans: A Randomized, Double-Blind, Placebo-controlled Trial.
K. Hamazaki1, M. Itomura1, S. Watanabe1, T. Hamazaki1, K. Terasawa1, S. Nakajima2, 1Toyama Medical and Pharmaceutical University, Japan, 2Nippon Suisan Kaisha, Ltd., Japan
N-2: EPA and DHA Increase Chylomicron Triglyceride Clearance in Humans.
W.S. Harris and Y. Park, University of Missouri, USA
N-3: Omega-3 Supplementation Improves Drug-Treatment of Hyperlipidaemia.
P. Howe1, T.Hammervold2, B. Meyer1, A. Rustan2 and D. Calvert1, 1University of Wollongong, Australia;
2 University of Oslo, Norway
N-4: Vasodilator and Hypolipidemic Effects of Hawthorn Fruit Extract.
Y. Huang, Z. Chen, Chinese University of Hong Kong, P.R. China
N-5: Evaluation of Cardiovascular Risk Factors in Hyperlipidemic Subjects Taking an Omega-3 Supplement Together with Soy Isoflavones.
L. Ridges, G. Martin, T. Larkin, B. Meyer and P. Howe, University of Wollongong, Australia
N-6: Exploring the Mechanism for Triglyceride-Rich Lipoprotein-Mediated Inhibition of Cholesterol Efflux from Macrophage Foam Cells.
A.M. Palmer1, N. Murphy2, A. Graham2, 1The University of Reading, 2Royal Free and University College, UK
SESSION O: POLYUNSATURATES AND NEUROLOGICAL FUNCTION
Chair: Robert Katz, Omega-3 Research Institute, Inc., USA
O-1: Effects of Dietary Intake of Long Chain n-3 and n-6 Polyunsaturated Fatty Acids on Short Term Memory in Rats.
M. Lutz, C. Barra, A. Palacios, Universidad de Valparaíso, Chile
O-2: Relationship Between Docosahexaenoic Acid (22:6n-3) in Cerebral Membranes and Neurophysiological Functions in the Rat.
C. Poumès-Ballihaut1, J. Cluzel2, S. Chalon3, L. Bussière4, P.Guesnet1 , 1INRA, 2Université d’Auvergne2, Clermont-Ferrand, 3INSERM U316, France, 4Blédina s.a., Danone, France
O-3: Alterations in Behavior and Neuroanatomy in DHA Deficient Rats.
N. Salem, Jr.1, R.F. Mervis2, A. Ahmad1, T. Moriguchi1, J. Nicklay1, R. Greiner1, S. Lim1, A. Bachstetter2 and B. Slotnick3, 1NIAAA, NIH, USA; 2NeuroStructural Research Labs, USA; 3American University, USA
O-4: The Recovery of Brain Docosahexaenoate Subsequent to Dietary N-3 Fatty Acid Insufficiency Leads to Recovery of Spatial Task Performance.
T. Moriguchi and N. Salem Jr, LMBB/NIAAA/NIH, USA
O-5: Less Mature Infant CNS in Gestational Diabetes Mellitus (GDM): Nutrition and Pregnancy Sleep Study at Storrs.
Carol J. Lammi-Keefe, Susanna Farkas, Sunita R. Cheruku, Hawley E. Montgomery-Downs, Charlotte I. DeMare, Melissa R. Keplinger, Elizabeth D. Loosemore, Evelyn B. Thoman, University of Connecticut, USA.
O-6: Effect of Various Linoleic Acid (LA) and Alpha-Linolenic Acid (ALA) Intakes on Growth, Energy Expenditure, and Body Composition of Term Infants.
Alexandre Lapillonne1, Craig L Jensen1, J Kennard Fraley1, Steven D. Clarke2 and William C Heird1. 1Pediatrics, Baylor College of Medicine, 2Nutrition, Cellular and Molecular Sciences, University of Texas, USA
SESSION P: DESATURATION-CHAIN ELONGATION
Chair: Vasuki Wijendran, Brandeis University, USA
P-1: Components of Cigarette Smoke Inhibit the Biosynthesis of Long Chain Polyunsaturated Fatty Acids in Human Mammary Epithelial Cells.
F. Marangoni, C. Colombo and C. Galli, University of Milan, Italy
P-2: Effects of a Novel Delta-6 Desaturase Inhibitor on Blood Pressure and PUFA Biosynthesis in Spontaneously Hypertensive Rats.
M.M. Narce, J.F. Merlin, S. Bellenger, J. Bellenger, and J.P. Poisson, Université de Bourgogne, France
P-3: Investigation of a Promoter Mutational Event Responsible for the Decreased Fatty Acid ?6 Desaturase Expression in a Mutant Human Skin Fibroblast Cell Line.
J.O. Nwankwo, F.E. Domann and A.A. Spector, University of Iowa, USA
P-4: The Same Rat δ6-Desaturase Not Only Acts on 18- but also on 24-Carbon Fatty Acids in Very-Long-Chain Polyunsaturated Fatty Acid Biosynthesis.
S. D'Andréa, H. Guillou, S. Jan, V. Rioux, and P. Legrand, Laboratoire de Biochimie ENSAR-INRA, France
P-5: Effect of the δ6-Desaturase Inhibitor Sc-26196 on Polyunsaturated Fatty Acid Metabolism in Human Cells.
A.A. Spector, Shawn Harmon, Terry Kaduce, Joseph Nwankwo, Tony Manuel, University of Iowa, USA
P-6: Upregulation of the N-6 Polyunsaturated Fatty Acid Biosynthetic Pathway in Pancreatic Exocrine Cells from Cftr -/- Mice.
M. Ollero, P.G. Blanco, M. Zaman, O. Junaidi, J.G. Alvarez and S.D. Freedman, Beth Israel Deaconess Medical Center, USA
P-7: The Use of Genetic Approach to Optimize Essential Fatty Acid Composition: Gene Transfer of n-3 Desaturase.
Jing Kang, Massachusetts General Hospital, USA
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