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Sunday 27th June
14:00 - 17:30 ISSFAL 2004 Registration and poster mounting
18:00 - 19:30 ISSFAL 2004 Official opening and welcome reception
Welcome!
I am delighted to welcome you to the LCPUFAs and Maternal and Child Health Workshop in Brighton. This Workshop is a follow-up to previous successful conferences in Barcelona and Kansas City and weare delighted to be able to hold this meeting as a prelude to ISSFAL 2004. We hope that the programme provides an opportunity to extend our understanding of the relationship of LCPUFAs tocognitive function, and also to consider the emerging research on the possible roles of LCPUFAs in non-neural development. I am grateful to all the speakers who have kindly agreed to contribute and look forward to a lively and stimulating Workshop.
Professor Stewart Forsyth, Workshop Host.
We gratefully acknowledge financial support from the following organisations towards the staging of today's workshop:Numico Research Germany
NEW CONCEPTS / EMERGING RESEARCH
PROGRAMME
09:00 - 09:30 REGISTRATION
09:30 - 11:00 BEHAVIOUR AND LEARNINGChair: Professor Gerard Hornstra, Mastricht University, Netherlands
(1) PERINATAL DHA STATUS, EARLY FEEDING PRACTICE, AND PROBLEM BEHAVIOUR OF 7-YEAR-OLD CHILDREN
L. Krabbendam (1), E. Bakker (2), G. Hornstra (2), J. van Os (1), Departments of Psychiatry and
Neuropsychology (1) and Human Biology (2), Maastricht University, PO Box 616, 6200 MD
Maastricht, The Netherlands
(2) CORRELATION BETWEEN PLASMA (N-3) FATTY ACID LEVELS AND COGNITIVE PERFORMANCE IN WOMEN
R.H.M. de Groot1, G. Hornstra2, J. Jolles1. 1 Department of Psychiatry & Neuropsychology and
2 Nutrition and Toxicology Research Institute Maastricht (NUTRIM), Maastricht University,
Maastricht, the Netherlands.
(3) THE LONG CHAIN POLYUNSATURATED FATTY ACIDS AND NEUROLOGICAL DEVELOPMENTAL OUTCOME AT 18 MONTHS IN HEALTHY TERM INFANTS FOLLOWED FROM BIRTH
Hylco Bouwstra1, D.A. Janneke Dijck-Brouwer2, Gunther Boehm3, E. Rudy Boersma4,
Frits A.J. Muskiet2, Mijna Hadders-Algra1. 1. Dept Neurology, University of Groningen. 2. Pathology and Laboratory Medicine, University Hospital Groningen. 3. Numico Research Germany, Friedrichsdorf 4. Perinatal Nutrition & Development Unit, Department of Paediatrics/Obstetrics and Gynaecology, University of Groningen
(4) THE EFFECT OF AN OMEGA- RICH SPREAD ON THE COGNITIVE FUNCTION OF LEARNERS 6-9 YEARS OLD FROM A LOW SOCIO-ECONOMIC COMMUNITY
CM Smuts1, A. Dalton2, RC Witthuhn2, AJS Benade1
Nutritional Intervention Research Unit, MRC, Parow Valley and
Department of Food Science, University of Stellenbosch, Stellenbosch, South Africa.
(5) EFFECT OF DIETARY FISH OIL ON PUPPY TRAINABILITY
R.L. Kelley*, A.J. Lepine, J.R. Burr, M. Shyan-Norwalt, and G.A. Reinhart. The Iams Company Technical Centre, Lewisburg. OH 45338
11.20 - 12.30 POSTNATAL DEPRESSION
Chair: Dr Joe Hibbeln, NIAAA/NIA, Rockville, USA
CURRENT THOUGHTS ON LCPUFAs AND POSTNATAL DEPRESSION
Dr Joe Hibbeln, NIAAA/NIA, Rockville, USA
(6) SERUM DOCOSAHEXAENOIC ACID IS ASSOCIATED WITH SYMPTOMS OF POSTNATAL DEPRESSION
M Makrides1, CA Crowther2, RA Gibson1, RS Gibson3, CM Skeaff3, 1Child Health Research Institute, North Adelaide, SA 50062Dept Obstetrics & Gynaecology, University of Adelaide, SA 5005, 3Dept Human Nutrition, University of Otago, New Zealand.
(7) RELATIONSHIP OF POSTNATAL DEPRESSION TO PERINATAL LCPUFA STATUS
JS Forsyth, P Willatts, GJ Mires, PE Ross, University of Dundee, Scotland.
13:30 - 14:30 VASCULAR FUNCTION AND DIABETES
Chair: Professor Michael Crawford, University of North London, UK
(8) GESTATIONAL DIABETES REDUCES RED CELL AND INCREASES PLACENTAL ARACHIDONIC AND DOCOSAHEXAENOIC ACID LEVELS
1Bitsanis D, 1Ghebremeskel K, 1Moodley T, 2Djahanbakhch OB, 1Crawford MA. 1IBCHN, London Metropolitan University; 2Department of Obstetrics and Gynaecology, St. Bartholomew's Hospitaland The Royal London School of Medicine, London, UK
(9) BLOOD PRESSURE AND HEART RATE VARIABILITY IN CHILDREN 2 YEARS AFTER FISH OIL SUPPLEMENTATION OF THEIR LACTATING MOTHERS
L. Lauritzen1, J.H. Christensen2, & K.F. Michaelsen1.,Dept. Human Nutr., The Royal Vet and Agricult. Univ., Frederiksberg, and Dept. of Nephrology, Aalborg Hospital, Aalborg, Denmark.
(10) MATERNAL DIETARY ESSENTIAL FATTY ACID DEFICIENCY REGULATES THE MRNA EXPRESSION OF LEPTIN RECEPTORS IN SUCKLING RAT PUPS
Palsdottir V1, Gabrielsson BG2, Korotkova M1, Strandvik B1, Depts of Pediatrics1 and Internal medicin2 Sahlgrenska Academy, Göteborg University, Göteborg, Sweden
14:30 - 15:30 IMMUNE FUNCTION
Chair: Professor Philip Calder, University of Southampton, UK
LCPUFAs AND IMMUNE FUNCTION
Professor Philip Calder, University of Southampton, UK
(11) FISH OIL SUPPLEMENTATION OF LACTATING MOTHERS AFFECTS CYTOKINE PRODUCTION IN 21/2-YEAR-OLD CHILDREN
L.Lauritzen1, T.Kjær2, H.Frøkiær2, and K.F.Michaelsen1.,1Dept. Human Nutr., The Royal Vet. & Agricult. Univ., Frederiksberg, and 2BioCentrum, The Techn.Univ., Lyngby, Denmark
.
(12) DIFFERENT N-6 POLYUNSATURATED FATTY ACID COMPOSITION OF MILK FROM ALLERGIC AND NON-ALLERGIC MOTHERS
C. Beermann, A. Möller, J. Jelinek, G. Boehm
Numico Research, Friedrichsdorf, Germany.
15:50 - 16:30 INVITED LECTURE: SHOULD CHILDREN BE ROUTINELY SUPPLEMENTED WITH COD LIVER OIL?
Professor Robert Gibson, Flinders Medical Centre, Adelaide, Australia
16:30 Close
Assessing Coronary Heart Disease Risks with PUFA Biomarkers (International Workshop)
PROGRAMME
09:00-09:30 REGISTRATION
Morning Session:
Chairpersons:Professor Andrew J. Sinclair, RMIT University, Melbourne, Victoria, Australia andProfessor William S. HarrisMid America Heart Institute and University of Missouri-Kansas City, U.S.A.
09:30-09:40 WELCOME AND INTRODUCTION
Dr Robert Katz, Omega-3 Research Institute, Inc., Bethesda, Maryland, U.S.A.
09:40-10:10 CONVERTING A BIOMARKER INTO A RISK FACTOR
Professor Christine M Albert, Brigham and Women's Hospital and Harvard University Medical School, Cambridge, Massachusetts, U.S.A.
10:10-10:40 CLASSIC AND EMERGING RISK FACTORS FOR CHD
Professor Parveen Yaqoob, University of Reading, Reading, U.K.
10:40-11:10 PUFA AND RISK FACTORS FOR CHD
Professor Clemens von Schacky, University of Munich, Munich, Germany
11:40-12:10 THE N-6:N-3 PROPORTIONS IN DIET AND TISSUES: CHD RISK MARKERS?
Dr. William E. M. LandsRockville, Maryland, U.S.A.
12:10-12:40 RBC EPA+DHA: THE OMEGA-3 INDEX
Professor William S. Harris, Mid America Heart Institute and University of Missouri-Kansas City, U.S.A.
12:40-13:10 PANEL* DISCUSSION OF MORNING PRESENTATIONS
Discussion Leaders:
Professor, Arthur A. Spector, University of Iowa, Iowa City, Iowa, U.S.A. and Professor Trevor A. Mori, University of Western Australia, Perth, Western Australia
Afternoon Session:
Chairpersons: Professor Clemens von Schacky,University of Munich, Munich, Germany and Professor Christine Williams, School of Food Biosciences, University of Reading, U.K.
14:00-14:20 OIL QUALITY AND QUALITY CONTROL
Professor Robert G. Ackman, Dalhousie University, Halifax, Nova Scotia, Canada
14:20-15:30 HIGH THROUGHPUT ANALYSES FOR PLASMA AND RBC INTRODUCTION
Professor Andrew Sinclair, RMIT University, Melbourne, Victoria, Australia
ULTRA FAST GC AND ULTRA FAST GC/MS FOR THE ANALYSIS OF FATTY
ACID METHYL ESTER FROM VEGETABLE AND ANIMAL LIPIDS
Professor Luigi Mondello, Dipartimento Farmaco- Chimico, Facoltà di Farmacia, Università di Messina,Messina, Italy
FAST GC-FAME ANALYSES OF FISH OIL USING CONVENTIONAL COLUMNS
J.M.Curtis†, B.Tague†, S.Ryan†, M.Arsenault†, D.S.Waddell‡ and R.Wittrig*, †Ocean Nutrition Canada, Halifax, Nova Scotia Canada; ‡Pfizer Global Research &Development, Groton Laboratories Groton, CT, USA; *Restek Corporation, Bellefonte, PA, USA
FAST GC ANALYSIS OF FATTY ACID METHYL ESTERS AND CONCEPTS FOR AUTOMATED TRANSMETHYLATION REACTIONS
Norman Salem, Jr1, Ken D. Stark1, Athar Masood1 and Len Sidisky21 Laboratory of Membrane Biochemistry & Biophysics, NIAAA, NIHRockville, MD 20852 USA and 2. Supelco Park, Bellefonte, PA 16823
16:00-17:30 PANEL DISCUSSION:
Discussion leaders:Professor Andrew J. Sinclair, RMIT University, Melbourne, Victoria, Australia and Professor Christine M. Albert,Brigham and Women's Hospital and Harvard University Medical School, Cambridge, Massachusetts, U.S.A.
To develop consensus towards one or more useful biomarkers for predicting risk of developing CHD and/or dying from CHD.Developing and recommending guidelines for lowering the risk of death from CHD with n-3 LC PUFA supplementation.
17:30 Workshop concludes
Panel:Andrew J. Sinclair, Chair*; William S. Harris, Co-Chair;* Robert G. Ackman; ChristineM. Albert*; William E.M. Lands; Trevor A. Mori; Norman Salem*, Jr.,; Clemens von Schacky*; Arthur Spector; Christine Williams*; Parveen Yaqoob;Philip Calder*; Robert Katz*, Ph.D.
*Also Organizing Committee Member
The Organisers Gratefully Acknowledge Financial Support from the Following
Sponsors:
Council for Responsible Nutrition, U.S.A.
DSM Corporation
British Heart Foundation,
Pronova Biocare A.S.
BASF Corporation
Omega Protein Inc.
Monsanto Company
Ocean Nutrition Canada
Nu-Mega Ingredients Pty Ltd, Australia
Endorsement By:
American Heart Association, U.S.A.
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